Pyrrolizidine alkaloids in plants used in the traditional medicine of Madagascar and the Mascarene islands.

作者: E Roeder , H Wiedenfeld

DOI:

关键词:

摘要: Pyrrolizidine alkaloids (PAs) can be hazardous to the health of humans and animals. Although their toxicity has been known for a long time, PA containing plants are still in use many traditional medicines. Traditional healing systems have become increasing interest as people believe that they used without any risk side effects. This also applies medicine Madagascar Mascarene island (Mauritius, Reunion, Rodriguez). Recent literature reports recommended this because its good efficacy pharmacological properties. However, several listed there which already described contain toxic PAs or suspected them.

参考文章(64)
Liu Wc, Rao Kv, Kugelman M, Axelrod M, McBride Tj, Indicine-N-oxide: the antitumor principle of Heliotropium indicum. Lloydia. ,vol. 39, pp. 125- 128 ,(1976)
Fumiko ABE, Tatsuo YAMAUCHI, Shiryo YAGA, Kazuo MINATO, Pyrrolizidine alkaloids from Parsonsia laevigata in okinawa Island (studies on Parsonsia. V) Chemical & Pharmaceutical Bulletin. ,vol. 39, pp. 1576- 1577 ,(1991) , 10.1248/CPB.39.1576
L. B. Bull, C. C. J. Culvenor, A. T. Dick, The pyrrolizidine alkaloids. Their chemistry, pathogenicity and other biological properties. The pyrrolizidine alkaloids. Their chemistry, pathogenicity and other biological properties.. ,(1968)
Fumiko ABE, Tsuneatsu NAGAO, Hikaru OKABE, Tatsuo YAMAUCHI, Nobuhiro MARUBAYASHI, Ikuhiko UEDA, Parsonsianine, a Macrocyclic Pyrrolizidine Alkaloid from the Leaves of Parsonsia laevigata (Studies on Parsonsia, III) Chemical & Pharmaceutical Bulletin. ,vol. 38, pp. 2127- 2129 ,(1990) , 10.1248/CPB.38.2127
R. J. Molyneux, Roger A. Coulombe Jr., D. L. Gardner, T. K. Schoch, S. M. Colegate, J. A. Edgar, B. L. Stegelmeier, Pyrrolizidine alkaloid plants, metabolism and toxicity. Journal of Natural Toxins. ,vol. 8, pp. 95- 116 ,(1999)
Philippe Beaujard, Plantes et medecine traditionnelle dans le Sud-Est de Madagascar Journal of Ethnopharmacology. ,vol. 23, pp. 165- 265 ,(1988) , 10.1016/0378-8741(88)90004-9
PH Canter, Medicinal and Aromatic Plants of Indian Ocean Islands Focus on Alternative and Complementary Therapies. ,vol. 9, pp. 164- 165 ,(2010) , 10.1111/J.2042-7166.2004.TB04307.X
Julia W. Novy, Medicinal plants of the eastern region of Madagascar Journal of Ethnopharmacology. ,vol. 55, pp. 119- 126 ,(1997) , 10.1016/S0378-8741(96)01489-4