Tumours of the Nervous System: an Ultrastructural Atlas

摘要: Since the time of earliest electron microscopic studies on tumours human nervous system. undertaken over 20 years ago by Luse and her colleagues. there have been considerable advances in our understanding these neoplasms. Tissue culture specific antibodies to tumour antigens are two techniques which greatly aided such advances. enabling much be learned about biological properties underly ing nature all types system tumour. Electron microscopy. however. has continued prove value investigation tumours. technological last decades dramatically improved resolution overall quality ultrastructural images obtained. In clinical neuropathology. improvements encouraged a more widespread use microscope diagnosis alongside antibody conventional histological methods. Although examination is often not strictly necessary identify well-differentiated as astrocytomas or choroid plexus papillomas. study features cases fre quently proves useful their malignant counterparts. Thus recognition astrocytic filaments anaplastic gliomas. cilia pleomorphic carcinomas. may enable made where insufficient differentiation for recognised at light level."