摘要: PURPOSE OF REVIEW To summarize the emerging data on risk factors for Barrett's esophagus and stratification tools. RECENT FINDINGS Obesity, particularly abdominal obesity, is associated with esophagus, likely because of both mechanical effects promoting gastroesophageal reflux nonmechanical effects. Circulating peptides related to obesity alter may work synergistically reflux. Tobacco use an underappreciated esophagus. A number genetic variants have been involving pathways in esophageal development. Risk tools are becoming available that modest discriminatory capability good calibration. SUMMARY The developing understanding shifting clinical guidelines a nuanced approach incorporating multiple select patients screening