Clinical analysis of 45 patients with malignant pleural mesothelioma

摘要: Background and objective Malignant pleural mesothelioma (MPM) is a rare tumor with increasing incidence, its early diagnoses treatments are difficult. The aim of the current study to investigate clinical features, diagnoses, MPM, provide reference for use. Methods A total 45 MPM patients admitted in Chinese PLA General Hospital from January 1997 December 2010 their records were analyzed retrospectively. Results major symptoms included: chest pain (53.33%), distress (48.89%) cough (37.78%). CT manifestations thickening (71.11%), effusion (60%) lung shadow (40%). fluid was exudative. number nucleated cells increased, most which mononuclear cells. Moreover, lactic acid dehydrogenase (LDH) levels culture medium significantly increased. common stage either III or IV. Thoracoscopy one main diagnosis methods, epithelium cell type pathologic type. In addition, easily misdiagnosed as tuberculous pleurisy. Patients an mainly cured through surgery, whereas chemotherapy applied advance stage. disease control rate epithelial higher than that fibrosarcoma Conclusion misdiagnosis high because have untypical symptoms. However, scan can important basis MPM. accurate based on pathological examinations immunohistochemistry. methods treatment include chemotherapy, surgical operation, radiotherapy supportive treatment. these still insufficient require further studies. DOI: 10.3779/j.issn.1009-3419.2012.02.06