Species-Specific Inhalation Pharmacokinetics of 2-Nitropropane, Methyl Ethyl Ketone, and n-Hexane
作者： Winfried Kessler , Barbara Denk , Johannes G. Filser
DOI: 10.1007/978-1-4684-5625-7_10
关键词:
摘要: 2-Nitropropane (2-NP), methyl ethyl ketone (MEK), and n-hexane (HEX) are used in large quantities for industrial processes. They components of solvent mixtures present as thinners commercial products like glues, paints, laquers. Because their high volatility persons mainly exposed via inhalation the vapors.
springer.com
sci-hub.st 参考文章(52)
D Carter Anthony, Kim Boekelheide, Doyle G Graham, None, The effect of 3,4-dimethyl substitution on the neurotoxicity of 2,5-hexanedione: I. Accelerated clinical neuropathy is accompanied by more proximal axonal swellings Toxicology and Applied Pharmacology. ,vol. 71, pp. 362- 371 ,(1983) , 10.1016/0041-008X(83)90023-6
D Carter Anthony, Kim Boekelheide, C William Anderson, Doyle G Graham, None, The effect of 3,4-dimethyl substitution on the neurotoxicity of 2,5-hexanedione. II. Dimethyl substitution accelerates pyrrole formation and protein crosslinking. Toxicology and Applied Pharmacology. ,vol. 71, pp. 372- 382 ,(1983) , 10.1016/0041-008X(83)90024-8
J. G. Filser, H. M. Bolt, Inhalation pharmacokinetics based on gas uptake studies Archives of Toxicology. ,vol. 52, pp. 123- 133 ,(1983) , 10.1007/BF00354772
J V Bruckner, G J Traiger, The participation of 2-butanone in 2-butanol-induced potentiation of carbon tetrachloride hepatotoxicity. Journal of Pharmacology and Experimental Therapeutics. ,vol. 196, pp. 493- 500 ,(1976)
U. Andrae, L. Vogl, J. Lichtmannegger, K.H. Summer, 2-Nitropropane induces DNA repair synthesis in rat hepatocytes in vitro and in vivo. Carcinogenesis. ,vol. 9, pp. 811- 815 ,(1988) , 10.1093/CARCIN/9.5.811
Peter S. Spencer, Monica C. Bischoff, Herbert H. Schaumburg, On the specific molecular configuration of neurotoxic aliphatic hexacarbon compounds causing central-peripheral distal axonopathy☆ Toxicology and Applied Pharmacology. ,vol. 44, pp. 17- 28 ,(1978) , 10.1016/0041-008X(78)90280-6
Travis B. Griffin, Frederick Coulston, Arthur A. Stein, Chronic inhalation exposure of rats to vapors of 2-nitropropane at 25 ppm Ecotoxicology and Environmental Safety. ,vol. 4, pp. 267- 281 ,(1980) , 10.1016/0147-6513(80)90029-9
A DAHL, Uptake of 19 hydrocarbon vapors inhaled by F344 rats Fundamental and Applied Toxicology. ,vol. 10, pp. 262- 269 ,(1988) , 10.1016/0272-0590(88)90310-7
KYOKO SAIDA, JERRY R. MENDELL, HAROLD S. WEISS, Peripheral nerve changes induced by methyl n-butyl ketone and potentiation by methyl ethyl ketone. Journal of Neuropathology and Experimental Neurology. ,vol. 35, pp. 207- 225 ,(1976) , 10.1097/00005072-197605000-00001
Anthony P. DeCaprio, Robert G. Briggs, Stephen J. Jackowski, James C.S. Kim, Comparative neurotoxicity and pyrrole-forming potential of 2,5-hexanedione and perdeuterio-2,5-hexanedione in the rat Toxicology and Applied Pharmacology. ,vol. 92, pp. 75- 85 ,(1988) , 10.1016/0041-008X(88)90229-3