Serum dehydroepiandrosterone sulfate concentration is lower in women with primary aldosteronism
作者： Ai-Hua Chen , Hung-Yuan Li , Vin-cent Wu , Yen-Hung Lin , Tien-Shang Huang
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摘要: Objective:The objective of this article is to measure serum dehydroepiandrosterone sulfate (DHEA-S) concentration in both genders with primary aldosteronism (PA).Materials and methods:The study enrolled 78 subjects normal controls, 46 essential hypertension 85 PA from October 2007 June 2011. Subjects were divided into three subtype groups: aldosterone-producing adenoma (APA), bilateral idiopathic hyperplasia (IHA) negative imaging findings.Results:Women (n = 49) had lower DHEA-S levels compared controls (p < 0.01). In analysis, only female APAs 0.01 p hypertension). APA, a significant correlation between tumor size was found women 0.01).Conclusion:Our data suggested that are PA. groups,...
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Abdulmaged M. Traish, H. Paco Kang, Farid Saad, Andre T. Guay, Dehydroepiandrosterone (DHEA)—A Precursor Steroid or an Active Hormone in Human Physiology (CME) The Journal of Sexual Medicine. ,vol. 8, pp. 2960- 2982 ,(2011) , 10.1111/J.1743-6109.2011.02523.X
Robert Hardin Williams, Henry Kronenberg, Williams Textbook of Endocrinology ,(2011)
Ann D. Nguyen, Alan J. Conley, Adrenal androgens in humans and nonhuman primates: production, zonation and regulation. Endocrine development. ,vol. 13, pp. 33- 54 ,(2008) , 10.1159/000134765
Y. Dong, P. Zheng, Dehydroepiandrosterone sulphate: action and mechanism in the brain. Journal of Neuroendocrinology. ,vol. 24, pp. 215- 224 ,(2012) , 10.1111/J.1365-2826.2011.02256.X
Gian Paolo Rossi, A comprehensive review of the clinical aspects of primary aldosteronism. Nature Reviews Endocrinology. ,vol. 7, pp. 485- 495 ,(2011) , 10.1038/NRENDO.2011.76
William E. Rainey, Yasuhiro Nakamura, Regulation of the adrenal androgen biosynthesis The Journal of Steroid Biochemistry and Molecular Biology. ,vol. 108, pp. 281- 286 ,(2008) , 10.1016/J.JSBMB.2007.09.015
V.-C. Wu, H.-W. Chang, K.-L. Liu, Y.-H. Lin, S.-C. Chueh, W.-C. Lin, Y.-L. Ho, J.-W. Huang, C.-K. Chiang, S.-Y. Yang, Y.-M. Chen, S.-M. Wang, K.-H. Huang, B.-S. Hsieh, K.-D. Wu, , Primary aldosteronism: diagnostic accuracy of the losartan and captopril tests. American Journal of Hypertension. ,vol. 22, pp. 821- 827 ,(2009) , 10.1038/AJH.2009.89
R. Oberbeck, P. Kobbe, Dehydroepiandrosterone (DHEA): a steroid with multiple effects. Is there any possible option in the treatment of critical illness? Current Medicinal Chemistry. ,vol. 17, pp. 1039- 1047 ,(2010) , 10.2174/092986710790820570
Xijun Cui, Lei Zhao, Shuang Chen, Tianyun Guan, Elizabeth J. Herrick, Bingbing Shi, Meifu Zang, Songsen Chen, Yujiang Fang, A potential role for CPY17 as a parameter in differentiation between aldosterone-producing adenoma and nodular hyperplasia in patients with hyperaldosteronism. Urology. ,vol. 79, ,(2012) , 10.1016/J.UROLOGY.2012.02.009
D. Flecchla, E. Mazza, M. Carllni, A. Blatto, F. Ollvlerl, G. Serra:, F. Camannl, M. Messlna, Reduced serum levels of dehydroepiandrosterone sulphate in adrenal incidentalomas: a marker of adrenocortical tumour Clinical Endocrinology. ,vol. 42, pp. 129- 134 ,(1995) , 10.1111/J.1365-2265.1995.TB01852.X