Effect of Harvest Time of Rickettsia rickettsii from Duck Embryo Cell Cultures on Rocky Mountain Spotted Fever Infection in the Rhesus Monkey.

作者： Duane E Hilmas , Gerald l Ruch

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摘要: Abstract : This study was undertaken to determine the optimum harvest time for infected duck embryo cell (DEC) cultures yield highest rickettsial titers and greatest infectivity rhesus monkeys. A consistently reproducible Rocky Mountain spotted fever-infected monkey model pathogenesis studies testing vaccine is produced when inoculum given intravenously contains =1000000 chick median lethal dose organisms. optimally attained with day-4 DEC culture material. (Author)

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Effect of Harvest Time of Rickettsia rickettsii from Duck Embryo Cell Cultures on Rocky Mountain Spotted Fever Infection in the Rhesus Monkey.

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Effect of Harvest Time of Rickettsia rickettsii from Duck Embryo Cell Cultures on Rocky Mountain Spotted Fever Infection in the Rhesus Monkey.

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