Pediatric low-grade gliomas: how modern biology reshapes the clinical field.
作者： Guillaume Bergthold , Pratiti Bandopadhayay , Wenya Linda Bi , Lori Ramkissoon , Charles Stiles
DOI: 10.1016/J.BBCAN.2014.02.004
关键词:
摘要: Low-grade gliomas represent the most frequent brain tumors arising during childhood. They are characterized by a broad and heterogeneous group of that currently classified WHO according to their morphological appearance. Here we review clinical features these tumors, current therapeutic strategies recent discovery genomic alterations characteristic tumors. We further explore how biological findings stand transform treatment for impact diagnostic criteria pediatric low-grade gliomas.
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