Prognostic significance of peritumoral lymphatic and blood vessel invasion in node-negative carcinoma of the breast.
作者： A K Lee , R A DeLellis , M L Silverman , G J Heatley , H J Wolfe
DOI: 10.1200/JCO.1990.8.9.1457
关键词:
摘要: The prognostic significance of intramammary lymphatic and blood vessel invasion was evaluated in a retrospective series 221 patients with node-negative carcinoma the breast treated modified radical mastectomy. To facilitate identification invasion, tumors were studied an immunohistochemical technique using antibodies to endothelial markers. Peritumoral (PLBI) (encompassing both invasion) adverse indicator independent menopausal status, tumor size, other histologic variables. Recurrence disease death resulting from significantly higher for PLBI-present (+) compared PLBI-absent (-) (P less than .0001). risk recurrence PLBI+ 4.7 times that their PLBI- counterparts. presence intratumoral (ILBI) is important because few ...
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