Predictive Factors for Node Metastasis in Patients With Clinical Stage I Non-Small Cell Lung Cancer

摘要: Background Accurate clinical staging of non-small cell lung cancer (NSCLC) is essential for developing a treatment plan and evaluating suitability minimally invasive surgery. The aim this study was to evaluate predictive factors metastasis N1 N2 nodes in stage I NSCLC. Methods Records patients with NSCLC who had undergone pulmonary resection systematic node dissection or sampling between 2003 2011 were retrospectively reviewed. To identify metastasis, univariate multivariate logistic regression analyses performed. Results Among the 770 study, overall prevalence 19.4%, which included 11.3% 8.1% nodes. Predictive male sex, current smoker, non-adenocarcinoma, solid consistency, centrally located tumor, T stage, cytokeratin fragment 21-1 level, tumor size, maximum standardized uptake value mass, ground-glass opacity proportion. Adenocarcinoma, carcinoembryonic antigen proportion identified as predictors metastasis. Both size consistency independent values by analysis. Conclusions NSCLC, 19.4% showed unexpected large Preoperative should be performed more thoroughly increase accuracy preoperative staging, especially those have larger tumor.