Acute Corticospinal Tract Wallerian Degeneration Is Associated With Stroke Outcome
作者： Giselle DeVetten , Shelagh B. Coutts , Michael D. Hill , Mayank Goyal , Muneer Eesa
DOI: 10.1161/STROKEAHA.109.573287
关键词:
摘要: Background and Purpose— In children with stroke, poor motor outcome is associated early Wallerian degeneration of the corticospinal tract that seen on diffusion-weighted MRI. this study we test hypothesis diffusion changes also occur in (CST) adults after stroke these lesions are outcome. Methods— retrospective study, assessed images from a serial MRI acute middle cerebral/internal carotid artery stroke. MRI-negative TIA patients served as controls. Custom software measured signal along CST different sequences, including apparent coefficient (ADC). Visual detection abnormal by blinded neuroradiologists was evaluated. We then determined associations between 3-month (NIHSS score). Results— Thirty-eight (20 stroke/18 control) were included. ADC measures much more accurate than other sequences for detection...
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