Long-term outcomes of malignant phyllodes tumors patients: an institutional experience.

摘要: Abstract Background Malignant phyllodes tumors are an extremely rare breast tumor. Prognostic features and overall survival data have not been consistent across studies. Methods Retrospectively, we examined the clinicopathologic of 27 cancer patients treated for malignant from 1995 to 2004 analyzed their recurrence outcomes using contingency tables, a logistic regression model, or proportional hazard model. Results The mortality rate was 12% (n = 3) cohort 75% group with distant metastases. median follow-up period 51 months (range, 12–192 mo). A mitotic index greater than 10 per high-powered field, presence stromal overgrowth, mastectomy at initial surgery, larger tumor size were associated increased incidence Larger also death. Conclusions Most will enjoy significant long-term if appropriately local excision clear margins.