Bone marrow investigation with technetium-99m microcolloid and magnetic resonance imaging in patients with malignant myelolympho-proliferative diseases

摘要: In 63 patients with primary extramedullary malignant lymphoma or plasmacytoma, a study was performed in order to evaluate bone marrow involvement. All underwent 99mTc microcolloid whole body imaging (scintigraphy), using gamma camera interfaced computer, followed by nuclear magnetic resonance (MRI), (1.5 Tesla). MR images were made of the lumbosacral region, pelvic both femoral and other parts skeleton, according focal lesions scintigraphy. A posterior iliac crest biopsy used as standard reference. present study, scintigraphy MRI showed dissiminated involvement combination both. 53 (84%) results accordance. Pathological signals pathological findings did not always correspond tumorous involvement, shown reflect reactive changes central part skeleton periphery radionuclide extention interpreted compensatory hematopoietic proliferation. The negative predictive value 92% 100%, respectively. When combining examinations, positive increased from 49% 58%, if is accepted gold standard. indicate that investigation simultaneously superior use either methods alone traditional biopsy.