Magnesium supplementation during pregnancy: a double-blind randomized controlled clinical trial.

作者: Baha M. Sibai , Marco A. Villar L , Eileen Bray

DOI: 10.1016/0002-9378(89)90246-9

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摘要: Four hundred young normotensive primigravid women between 13 and 24 weeks' gestation were randomly allocated to one of two study groups. One group received placebo tablets the other 365 mg elemental magnesium daily (as aspartate hydrochloride). Three seventy-four patients completed study, 189 in 185 treatment group. There no significant differences groups regarding serum calcium, uric acid, or electrolyte levels. However, magnesium-supplemented had significantly higher levels at delivery (1.68 ± 0.03 mg/dl vs. 1.56 mg/dl, p

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