Trastuzumab: More than a Guide in HER2-Positive Cancer Nanomedicine.

作者: Celia Nieto , Milena A. Vega , Eva M. Martín del Valle

DOI: 10.3390/NANO10091674

关键词:

摘要: … Thus, T-DM1 is integrated by a non-cleavable linker that allows the attachment of a derivative of maytansine (DM1) to Tmab [24,81]. Maytansine, which is a natural inhibitor of tubulin …

参考文章(108)
F.J. Martin, D. Papahadjopoulos, Irreversible coupling of immunoglobulin fragments to preformed vesicles. An improved method for liposome targeting. Journal of Biological Chemistry. ,vol. 257, pp. 286- 288 ,(1982) , 10.1016/S0021-9258(19)68359-6
Rita Nahta, Francisco J Esteva, HER2 therapy: Molecular mechanisms of trastuzumab resistance Breast Cancer Research. ,vol. 8, pp. 215- 215 ,(2006) , 10.1186/BCR1612
Robin C. Humphreys, Jessica Kirtely, Amha Hewit, Sandra Biroc, Nick Knudsen, Lillian Skidmore, Alan Wahl, Abstract 639: Site specific conjugation of ARX-788, an antibody drug conjugate (ADC) targeting HER2, generates a potent and stable targeted therapeutic for multiple cancers Cancer Research. ,vol. 75, pp. 639- 639 ,(2015) , 10.1158/1538-7445.AM2015-639
Xuejing Yao, Jing Jiang, Xin Wang, Changjiang Huang, Dong Li, Kuan Xie, Qiaoyu Xu, Hongwen Li, Zhuanglin Li, Liguang Lou, Jianmin Fang, A novel humanized anti-HER2 antibody conjugated with MMAE exerts potent anti-tumor activity. Breast Cancer Research and Treatment. ,vol. 153, pp. 123- 133 ,(2015) , 10.1007/S10549-015-3503-3
Akila Kesavan, P. Ilaiyaraja, W. Sofi Beaula, Vuttaradhi Veena Kumari, J. Sugin Lal, C. Arunkumar, G. Anjana, Satish Srinivas, Anita Ramesh, Suresh Kumar Rayala, D. Ponraju, Ganesh Venkatraman, Tumor targeting using polyamidoamine dendrimer–cisplatin nanoparticles functionalized with diglycolamic acid and herceptin European Journal of Pharmaceutics and Biopharmaceutics. ,vol. 96, pp. 255- 263 ,(2015) , 10.1016/J.EJPB.2015.08.001
Hans K. Erickson, Peter U. Park, Wayne C. Widdison, Yelena V. Kovtun, Lisa M. Garrett, Karen Hoffman, Robert J. Lutz, Victor S. Goldmacher, Walter A. Blättler, Antibody-Maytansinoid Conjugates Are Activated in Targeted Cancer Cells by Lysosomal Degradation and Linker-Dependent Intracellular Processing Cancer Research. ,vol. 66, pp. 4426- 4433 ,(2006) , 10.1158/0008-5472.CAN-05-4489
Bradley Duncan, Chaekyu Kim, Vincent M. Rotello, Gold nanoparticle platforms as drug and biomacromolecule delivery systems. Journal of Controlled Release. ,vol. 148, pp. 122- 127 ,(2010) , 10.1016/J.JCONREL.2010.06.004
Gail D. Lewis Phillips, Guangmin Li, Debra L. Dugger, Lisa M. Crocker, Kathryn L. Parsons, Elaine Mai, Walter A. Blättler, John M. Lambert, Ravi V.J. Chari, Robert J. Lutz, Wai Lee T. Wong, Frederic S. Jacobson, Hartmut Koeppen, Ralph H. Schwall, Sara R. Kenkare-Mitra, Susan D. Spencer, Mark X. Sliwkowski, Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody–Cytotoxic Drug Conjugate Cancer Research. ,vol. 68, pp. 9280- 9290 ,(2008) , 10.1158/0008-5472.CAN-08-1776
Jayeeta Banerjee, Marit Nilsen-Hamilton, Aptamers: multifunctional molecules for biomedical research. Journal of Molecular Medicine. ,vol. 91, pp. 1333- 1342 ,(2013) , 10.1007/S00109-013-1085-2