Enzymatic synthesis of some Wax‐esters

摘要: The Mucor miehei lipase, immobilized on a macroporous anion-exchange resin (Lipozyme TM), was used to catalyze esterification and interesterification for the synthesis of wax-esters. first series saturated esters, from 20 28 carbon atoms, were obtained with more than 80% yield. These esters are liquid up 24 atoms. Monounsaturated wax-esters 36 synthesized yields greater 70%. With few exceptions all these compounds 34 Attempts alcoholysis involving ricinoleyl chain, revealed remarkable selectivity Lipozyme. Primary found be sole reaction products (yields 79 81,5%). It possible prepare diesters octanediol suberic acid good (84-92%). Unfortunately moderate in monoesters. 1,2-alkanediol monolaurates easily selectively synthesized, but low A fair amount secondary ester besides expected primary ester. mechanism an equilibrium between both via cyclic intermediate accounted acyl migration.