Hypoglycemic Effect of Chlorella sp. CMS-1 Hot Water Extract on Streptozotocin-Induced Diabetic Rats
作者： Jung-Wook Kim , Jae-Young Cha , Jin-Sun Heo , Hyun-Jin Jin , Young-Su Cho
DOI: 10.5352/JLS.2008.18.11.1584
关键词:
摘要: The effect of Chlorella hot water extract (CE) on hyperglycemia in streptozotocin- induced diabetic rats has not been studied. Therefore, hypoglycemic CE type I was Rats were fed a semisynthetic diet supplemented with either 3% (the STZ+CE3) and 6% STZ+CE6) or no supplement the Normal STZ-Control for 4 weeks. concentrations fasting non-fasting blood glucose higher than rats, but this rise lowered STZ+CE3 STZ+CE6 rats. Serum insulin decreased STZ injection, however, levels almost restored to level supplementation. increased serum fructosamine associated treatment. morphology pancreatic islets rat round maintained typical arrangement. beta-cells found have significant swelling severely morphological damaged, tissue damage by CE-supplemented group ameliorated. This study shows that had STZ-diabetic via secretion during recovery prevention STZ-induced damage.
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