X-ray-induced shortwave infrared biomedical imaging using rare-earth nanoprobes.
作者： Dominik Jan Naczynski , Conroy Sun , Silvan Türkcan , Cesare Jenkins , Ai Leen Koh
DOI: 10.1021/NL504123R
关键词:
摘要: Shortwave infrared (SWIR or NIR-II) light provides significant advantages for imaging biological structures due to reduced autofluorescence and photon scattering. Here, we report on the development of rare-earth nanoprobes that exhibit SWIR luminescence following X-ray irradiation. We demonstrate the ability of X-ray-induced SWIR luminescence (X-IR) to monitor biodistribution and map lymphatic drainage. Our results indicate X-IR imaging is a promising new modality for preclinical applications and has potential for dual …
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