Men of Higher Socioeconomic Status Have Improved Outcomes After Radical Prostatectomy for Localized Prostate Cancer

作者: Nicholas J. Hellenthal , Arti Parikh-Patel , Katrina Bauer , W. Ralph , White deVere

DOI: 10.1016/J.UROLOGY.2010.03.024

关键词:

摘要: OBJECTIVE We sought to evaluate the impact of socioeconomic status (SES) on likelihood undergoing radical prostatectomy (RP) or external beam radiation therapy (XRT) and ensuing effect cancer-specific survival (CSS) after treatment for men with low-risk prostate cancer. METHODS Using California Cancer Registry database, we identified 123,953 diagnosed localized, Gleason ≤7 cancer from 1996 2005. Patients were separated into quintiles based stratified by race, age, year diagnosis, treatment. Logistic regression Kaplan-Meier analyses used determine RP XRT survival. RESULTS In final cohort, 39,234 patients (31.7%) 42,431 (34.3%) underwent as initial therapy. Men lower SES less likely undergo XRT. in lowest twice die (HR 1.99, 95% CI 1.28-3.09, P = .002) than highest SES. This difference was even more profound when adjusted race 2.20, 1.38-3.50, .001). Similarly, who also approximately 2.24, 1.71-2.94, <.001) SES, regardless race. CONCLUSIONS are management localized After XRT, have a decreased compared higher

参考文章(13)
Kathleen Yost, Carin Perkins, Richard Cohen, Cyllene Morris, William Wright, Socioeconomic status and breast cancer incidence in California for different race/ethnic groups. Cancer Causes & Control. ,vol. 12, pp. 703- 711 ,(2001) , 10.1023/A:1011240019516
John K. Chan, Mallory Zhang, Jessica M. Hu, Jacob Y. Shin, Kathryn Osann, Daniel S. Kapp, Racial disparities in surgical treatment and survival of epithelial ovarian cancer in United States. Journal of Surgical Oncology. ,vol. 97, pp. 103- 107 ,(2008) , 10.1002/JSO.20932
Stephen A. Mangar, Robert A. Huddart, Christopher C. Parker, David P. Dearnaley, Vincent S. Khoo, Alan Horwich, Technological advances in radiotherapy for the treatment of localised prostate cancer European Journal of Cancer. ,vol. 41, pp. 908- 921 ,(2005) , 10.1016/J.EJCA.2004.12.028
Ahmedin Jemal, Limin X. Clegg, Elizabeth Ward, Lynn A. G. Ries, Xiaocheng Wu, Patricia M. Jamison, Phyllis A. Wingo, Holly L. Howe, Robert N. Anderson, Brenda K. Edwards, Annual report to the nation on the status of cancer, 1975-2001, with a special feature regarding survival Cancer. ,vol. 101, pp. 3- 27 ,(2004) , 10.1002/CNCR.20288
Maureen Sanderson, Ann L. Coker, Adriana Perez, Xianglin L. Du, Gerson Peltz, Mary k. Fadden, A Multilevel Analysis of Socioeconomic Status and Prostate Cancer Risk Annals of Epidemiology. ,vol. 16, pp. 901- 907 ,(2006) , 10.1016/J.ANNEPIDEM.2006.02.006
Simon Evans, Chris Metcalfe, Fowzia Ibrahim, Raj Persad, Yoav Ben-Shlomo, Investigating Black-White differences in prostate cancer prognosis: A systematic review and meta-analysis. International Journal of Cancer. ,vol. 123, pp. 430- 435 ,(2008) , 10.1002/IJC.23500
Tracey L. Krupski, Lorna Kwan, Abdelmonem A. Afifi, Mark S. Litwin, Geographic and Socioeconomic Variation in the Treatment of Prostate Cancer Journal of Clinical Oncology. ,vol. 23, pp. 7881- 7888 ,(2005) , 10.1200/JCO.2005.08.755
Xianglin L. Du, Shenying Fang, Ann L. Coker, Maureen Sanderson, Corrine Aragaki, Janice N. Cormier, Yan Xing, Beverly J. Gor, Wenyaw Chan, Racial disparity and socioeconomic status in association with survival in older men with local/regional stage prostate carcinoma: findings from a large community-based cohort. Cancer. ,vol. 106, pp. 1276- 1285 ,(2006) , 10.1002/CNCR.21732
A. S. Robbins, D. Yin, A. Parikh-Patel, Differences in Prognostic Factors and Survival among White Men and Black Men with Prostate Cancer, California, 1995–2004 American Journal of Epidemiology. ,vol. 166, pp. 71- 78 ,(2007) , 10.1093/AJE/KWM052