De novo alveolar bone formation adjacent to endosseous implants: A model study in the dog

摘要: Abstract: Objective: To describe a model for the investigation of different phases wound healing that are involved in process resulting osseointegration. Material and methods: The implants used study early had geometry corresponded to solid screw implant with an SLA surface configuration. A circumferential trough been prepared within thread region (intra-osseous portion) established geometrically well-defined compartment. Twenty Labrador dogs received 160 experimental devices totally allow evaluation between 2 h 12 weeks. Both ground sections decalcified were from sites. Results: chamber appeared be conducive bone formation. provided overview various soft hard tissue formation, while decalcified, thin enabled more detailed events modeling remodeling. initially empty became occupied coagulum granulation was replaced by provisional matrix. formation started already during first week. newly formed present at lateral border cut bony bed continuous parent bone, but woven also found on distance bone. This primary included trabeculae parallel-fibered and/or lamellar marrow. Between 1 2 weeks, immediately pitch region, responsible mechanical stability device, resorbed viable Despite this temporary loss contact, remained clinically stable all times. Conclusion: Osseointegration represents dynamic both its establishment maintenance. In phase, there is delicate interplay resorption contact regions (between titanium body mineralized bone) ‘contact- free’ areas. During maintenance osseointegration secured through remodeling adaptation function.