The population structure of Staphylococcus aureus among general practice patients from The Netherlands

摘要: To investigate the prevalence, antibiotic resistance pattern and population structure of Staphylococcus aureus, S. aureus isolates from anterior nostrils patients general practitioners (GPs) were analysed. Insight into is essential, as nasal carriers are at increased risk developing an infection. was isolated swabs 2691 with no sign infection collected in 29 GP practices The Netherlands. susceptibility for several classes antibiotics determined, well genetic background, using spa typing. 617 (23%) swabs. prevalences to ciprofloxacin, co-trimoxazole, fusidic acid, macrolides mupirocin 0.2%, 0%, 6%, 5% 1%, respectively. Half associated a background common major methicillin-resistant (MRSA) clones, e.g. clonal complex (CC)1, CC5, CC8, CC22, CC30 CC45, remainder mainly CC7, CC12, CC15, CC26, CC51 CC101. low suggest that, Dutch situation, visiting their because complaints not related do represent large reservoir genes. Although MRSA found, some commonly observed among community-associated (CA)-MRSA clones (CC1, CC8 CC30), this might that these have potential become CA-MRSA.