Design and optimization of topical methotrexate loaded niosomes for enhanced management of psoriasis: application of Box-Behnken design, in-vitro evaluation and in-vivo skin deposition study.
作者： Aly A. Abdelbary , Mohamed H.H. AbouGhaly
DOI: 10.1016/J.IJPHARM.2015.03.020
关键词:
摘要: Psoriasis, a skin disorder characterized by impaired epidermal differentiation, is regularly treated by systemic methotrexate (MTX), an effective cytotoxic drug but with numerous side …
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