Treatment of secretory diarrhea in AIDS with the somatostatin analogue SMS 201-995.
作者： H. S. Füeßl , W. G. Zoller , M. M. Kochen , J. R. Bogner , B. Heinrich
DOI: 10.1007/BF01725142
关键词:
摘要: We have observed two patients with AIDS suffering from severe watery diarrhea refractory to conventional medical treatment. In the first patient reason for could not be revealed in spite of extensive investigations; however, clinical picture suggested cryptosporidia infection. second cytomegalovirus shown colonic biopsy specimens. After failure several attempts symptomatic, antibiotic, and antiviral therapy, long-acting somatostatin analogue SMS 201-995 was administered subcutaneously a dose between 2 x 50 micrograms 3 100 micrograms/day. This treatment resulted prompt reduction stool volume bowel motions. Somatostatin may useful addition symptomatic AIDS.
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