What outcome after the prescription of neoadjuvant chemotherapy in lung cancer

作者: Mohamed-Sadok Boudaya , Hanène Smadhi , Adel Marghli , Fatma Charmiti , Sonia Ouerghi

DOI: 10.1177/0218492312462576

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摘要: BackgroundThe treatment of patients with locally advanced non-small-cell lung cancer is controversial. Surgery remains the gold standard, even in this group. Neoadjuvant chemotherapy could allow surgical resection initially judged inoperable.MethodsFrom January 2009 to May 2010, neoadjuvant was indicated 27 NSCLC (25 men, 2 women). Their mean age 65 years. The stages were: IIB 5, IIIA 17 (6 stage IIIAN2), IIIB 2, and IV 3.Results23 received chemotherapy, refused induction treatment, had impaired status. regimen gemcitabine-cisplatin vinorelbine-cisplatin 6. Only 5 underwent complete after induction: 1 IIB, IIIAN0, IIIB, (1 operated brain metastasis, adrenal metastasis). Surgical not achieved 18 because progressive disea...

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