Nav1.5 regulates breast tumor growth and metastatic dissemination in vivo

作者: Michaela Nelson , Ming Yang , Rebecca Millican-Slater , William J. Brackenbury

DOI: 10.18632/ONCOTARGET.5441

关键词:

摘要: Voltage-gated Na+ channels (VGSCs) mediate action potential firing and regulate adhesion and migration in excitable cells. VGSCs are also expressed in cancer cells. In metastatic …

参考文章(57)
William J. Brackenbury, Mustafa B. A. Djamgoz, Activity-dependent regulation of voltage-gated Na+ channel expression in Mat-LyLu rat prostate cancer cell line The Journal of Physiology. ,vol. 573, pp. 343- 356 ,(2006) , 10.1113/JPHYSIOL.2006.106906
Carrie D. House, Bi-Dar Wang, Kristin Ceniccola, Russell Williams, May Simaan, Jacqueline Olender, Vyomesh Patel, Daniel T. Baptista-Hon, Christina M. Annunziata, J. Silvio Gutkind, Tim G. Hales, Norman H. Lee, Voltage-gated Na+ Channel Activity Increases Colon Cancer Transcriptional Activity and Invasion Via Persistent MAPK Signaling. Scientific Reports. ,vol. 5, pp. 11541- 11541 ,(2015) , 10.1038/SREP11541
Michaela Nelson, Rebecca Millican-Slater, Lorna C. Forrest, William J. Brackenbury, The sodium channel β1 subunit mediates outgrowth of neurite-like processes on breast cancer cells and promotes tumour growth and metastasis. International Journal of Cancer. ,vol. 135, pp. 2338- 2351 ,(2014) , 10.1002/IJC.28890
Jennet M. Harvey, Gary M. Clark, C. Kent Osborne, D. Craig Allred, Estrogen Receptor Status by Immunohistochemistry Is Superior to the Ligand-Binding Assay for Predicting Response to Adjuvant Endocrine Therapy in Breast Cancer Journal of Clinical Oncology. ,vol. 17, pp. 1474- 1474 ,(1999) , 10.1200/JCO.1999.17.5.1474
Lilly Y. W. Bourguignon, Hongbo Zhu, Lijune Shao, Yue-Wei Chen, CD44 Interaction with c-Src Kinase Promotes Cortactin-mediated Cytoskeleton Function and Hyaluronic Acid-dependent Ovarian Tumor Cell Migration * Journal of Biological Chemistry. ,vol. 276, pp. 7327- 7336 ,(2001) , 10.1074/JBC.M006498200
William J. Brackenbury, Voltage-gated sodium channels and metastatic disease. Channels. ,vol. 6, pp. 352- 361 ,(2012) , 10.4161/CHAN.21910
Daniel Diaz, Dulce Maria Delgadillo, Elizabeth Hernández‐Gallegos, Martha Eugenia Ramírez‐Domínguez, Luz María Hinojosa, Cindy Sharon Ortiz, Jaime Berumen, Javier Camacho, Juan Carlos Gomora, None, Functional expression of voltage-gated sodium channels in primary cultures of human cervical cancer. Journal of Cellular Physiology. ,vol. 210, pp. 469- 478 ,(2007) , 10.1002/JCP.20871
Sébastien Roger, Pierre Besson, Jean-Yves Le Guennec, Involvement of a novel fast inward sodium current in the invasion capacity of a breast cancer cell line Biochimica et Biophysica Acta (BBA) - Biomembranes. ,vol. 1616, pp. 107- 111 ,(2003) , 10.1016/J.BBAMEM.2003.07.001
Senay Yildirim, Seyhan Altun, Hatice Gumushan, Anup Patel, Mustafa B.A. Djamgoz, Voltage-gated sodium channel activity promotes prostate cancer metastasis in vivo. Cancer Letters. ,vol. 323, pp. 58- 61 ,(2012) , 10.1016/J.CANLET.2012.03.036
G. A. Papadatos, P. M. R. Wallerstein, C. E. G. Head, R. Ratcliff, P. A. Brady, K. Benndorf, R. C. Saumarez, A. E. O. Trezise, C. L.- H. Huang, J. I. Vandenberg, W. H. Colledge, A. A. Grace, Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a Proceedings of the National Academy of Sciences of the United States of America. ,vol. 99, pp. 6210- 6215 ,(2002) , 10.1073/PNAS.082121299