Interactions between Twist and other core epithelial–mesenchymal transition factors are controlled by GSK3-mediated phosphorylation

作者: Rachel Lander , Talia Nasr , Stacy D. Ochoa , Kara Nordin , Maneeshi S. Prasad

DOI: 10.1038/NCOMMS2543

关键词:

摘要: Twist is an epithelial–mesenchymal transition regulatory factor that implicated in neural crest development and cancer. Lander colleagues show interacts with Snail proteins to inhibit their function, this interaction regulated by phosphorylation of the C terminus.

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