Her2 extracellular domain.
作者： H. Michael Shepard , Robert Michael Hudziak , Axel Ullrich
DOI:
关键词:
摘要: An extracellular portion of the HER2 molecule, essentially free transmembrane and cytoplasmic portions, which is antigenic in animals. Isolated DNA encoding portion; an expression vector containing isolated DNA; a cell vector. A process for producing domain. vaccine
google.com.tr参考文章(57)
Drebin Ja, Link Vc, Greene Mi, Monoclonal antibodies reactive with distinct domains of the neu oncogene-encoded p185 molecule exert synergistic anti-tumor effects in vivo. Oncogene. ,vol. 2, pp. 273- ,(1988)
Toyoshima K, Sakamoto H, Nomura N, Yamamoto T, Terada M, Yoshida T, Yokota J, Sugimura T, Miyajima N, Genetic alterations of the c-erbB-2 oncogene occur frequently in tubular adenocarcinoma of the stomach and are often accompanied by amplification of the v-erbA homologue. Oncogene. ,vol. 2, pp. 283- 287 ,(1988)
John L. Cantrell, Vaccine containing tumor antigens and adjuvants ,(1987)
M.H. Kraus, N.C. Popescu, S.C. Amsbaugh, C.R. King, Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms The EMBO Journal. ,vol. 6, pp. 605- 610 ,(1987) , 10.1002/J.1460-2075.1987.TB04797.X
D S Duan, M J Pazin, L J Fretto, L T Williams, A functional soluble extracellular region of the platelet-derived growth factor (PDGF) beta-receptor antagonizes PDGF-stimulated responses. Journal of Biological Chemistry. ,vol. 266, pp. 413- 418 ,(1991) , 10.1016/S0021-9258(18)52450-9
William L. McGuire, Dennis J. Slamon, Determination of status in neoplastic disease ,(1986)
C Delisi, H Margalit, J L Cornette, J L Spouge, K B Cease, J A Berzofsky, Prediction of immunodominant helper T cell antigenic sites from the primary sequence. Journal of Immunology. ,vol. 138, pp. 2213- 2229 ,(1987)
Hector Battifora, Tadashi Yamamoto, Jun Yokota, Martin J. Cline, Dujin Zhou, Association of Multiple Copies of the c-erbB-2 Oncogene with Spread of Breast Cancer Cancer Research. ,vol. 47, pp. 6123- 6125 ,(1987)
Robert A. Weinberg, Cornelia I. Bargmann, Detection of point mutations in neu genes ,(1987)
M van de Vijver, R van de Bersselaar, P Devilee, C Cornelisse, J Peterse, R Nusse, Amplification of the neu (c-erbB-2) oncogene in human mammmary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene. Molecular and Cellular Biology. ,vol. 7, pp. 2019- 2023 ,(1987) , 10.1128/MCB.7.5.2019