High-frequency chest compression: effect of the third generation compression waveform.

摘要: High-frequency chest compression (HFCC) therapy has become the prevailing form of airway clearance for patients with cystic fibrosis (CF) in United States. The original square waveform was replaced 1995 a sine without published evidence an equality effectiveness. recent development triangle HFCC provided opportunity to compare functional and therapeutic effects different waveforms. Clinical testing done at home times recorded all sputum collected preweighed sealable vials. eight study CF were regular users device. They produced consistently clinically stable. used their optimum frequencies each and, one week waveform, during twice-daily timed therapies. After collection, these vials reweighed, desiccated, reweighed calculate wet dry weights per minute time. Frequency associated vest pressures transmitted mouth, induced airflows mouth measured healthy volunteers. pressure waveforms were, shape, faithfully demonstrable mouth. In subject transmission occurred 2 ms attenuated about 75% 60% waveform. All more than mean increase 20%+ range 4% 41%. P value <.001. Future studies should investigate other waveforms, as well neglected on mucus determine best disease, patient. (Biomedical Instrumentation & Technology 2004; 38:322–328).