Lowering Prolactin Level in a Hyperprolactinemic Man

作者: Jonathan L. Davis

DOI: 10.1001/ARCHINTE.1982.00340140148026

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摘要: • A 25-year-old man with hypogonadotropic hypogonadism and elevated prolactin levels, presumably from a microadenoma of the pituitary gland, was treated bromocriptine mesylate. After three weeks, level had fallen gonadotropin levels shown substantial rise, reaching supraphysiologic by eight eventually returning to normal 15 weeks. The serum testosterone did not rise until after weeks reached maximum When therapy stopped for one week, all indexes returned near pretreatment levels. Within two re-treatment bromocriptine, both rose. These findings suggest that may block secretion luteinizingreleasing hormone, or prevent gland responding it. ( Arch Intern Med 1982;142:146-148)

参考文章(8)
Fulgencio Gómez, Francisco I. Reyes, Charles Faiman, Nonpuerperal galactorrhea and hyperprolactinemia The American Journal of Medicine. ,vol. 62, pp. 648- 660 ,(1977) , 10.1016/0002-9343(77)90866-X
J.C. Roth, R.P. Kelch, S.L. Kaplan, M.M. Grumbach, FSH AND LH RESPONSE TO LUTEINIZING HORMONE-RELEASING FACTOR IN PREPUBERTAL AND PUBERTAL CHILDREN, ADULT MALES AND PATIENTS WITH HYPOGONADOTROPIC AND HYPERGONADOTROPIC HYPOGONADISM The Journal of Clinical Endocrinology and Metabolism. ,vol. 35, pp. 926- 930 ,(1972) , 10.1210/JCEM-35-6-926
MO Thorner, AS McNeilly, C Hagan, GM Besser, None, Long-term treatment of galactorrhoea and hypogonadism with bromocriptine. BMJ. ,vol. 2, pp. 419- 422 ,(1974) , 10.1136/BMJ.2.5916.419
David L. Kleinberg, Gordon L. Noel, Andrew G. Frantz, Galactorrhea: A Study of 235 Cases, Including 48 with Pituitary Tumors New England Journal of Medicine. ,vol. 296, pp. 589- 600 ,(1977) , 10.1056/NEJM197703172961103
A. PONT, Prolactin-Secreting Tumors in Men: Surgical Cure Annals of Internal Medicine. ,vol. 91, pp. 211- 213 ,(1979) , 10.7326/0003-4819-91-2-211
Willard Cates, David A. Grimes, Richard J. Haber, Carl W. Tyler, Abortion deaths associated with the use of prostaglandin F2α American Journal of Obstetrics and Gynecology. ,vol. 127, pp. 219- 222 ,(1977) , 10.1016/0002-9378(77)90456-2
John N. Carter, John E. Tyson, George Tous, Stuart Van Vliet, Charles Faiman, Henry G. Friesen, Prolactin-screening tumors and hypogonadism in 22 men. The New England Journal of Medicine. ,vol. 299, pp. 847- 852 ,(1978) , 10.1056/NEJM197810192991602