Double-stranded RNA induces inflammation via the NF-κB pathway and inflammasome activation in the outer root sheath cells of hair follicles.
作者： Jung-Min Shin , Dae-Kyoung Choi , Kyung-Cheol Sohn , Soo-Yeon Kim , Jeong Min Ha
DOI: 10.1038/SREP44127
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摘要: Alopecia areata (AA), a chronic, relapsing, hair-loss disorder, is considered to be a T cell-mediated autoimmune disease. It affects approximately 1.7% of the population, but its …
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Verena Kopfnagel, Miriam Wittmann, Thomas Werfel, Human keratinocytes express AIM2 and respond to dsDNA with IL-1β secretion. Experimental Dermatology. ,vol. 20, pp. 1027- 1029 ,(2011) , 10.1111/J.1600-0625.2011.01382.X
Fabio Martinon, Kimberly Burns, Jürg Tschopp, The Inflammasome Molecular Cell. ,vol. 10, pp. 417- 426 ,(2002) , 10.1016/S1097-2765(02)00599-3
Haitao Guo, Justin B Callaway, Jenny P-Y Ting, Inflammasomes: mechanism of action, role in disease, and therapeutics Nature Medicine. ,vol. 21, pp. 677- 687 ,(2015) , 10.1038/NM.3893
Taisuke ITO, Yoshiki TOKURA, Alopecia areata triggered or exacerbated by swine flu virus infection. Journal of Dermatology. ,vol. 39, pp. 863- 864 ,(2012) , 10.1111/J.1346-8138.2011.01437.X
Olaf Gross, Christina J. Thomas, Greta Guarda, Jurg Tschopp, The inflammasome: an integrated view Immunological Reviews. ,vol. 243, pp. 136- 151 ,(2011) , 10.1111/J.1600-065X.2011.01046.X
Maike Gold, Joseph El Khoury, β-amyloid, microglia, and the inflammasome in Alzheimer's disease. Seminars in Immunopathology. ,vol. 37, pp. 607- 611 ,(2015) , 10.1007/S00281-015-0518-0
U. Andersson, H. Rauvala, Introduction: HMGB1 in inflammation and innate immunity. Journal of Internal Medicine. ,vol. 270, pp. 296- 300 ,(2011) , 10.1111/J.1365-2796.2011.02430.X
Ai-Young Lee, Role of keratinocytes in the development of vitiligo. Annals of Dermatology. ,vol. 24, pp. 115- 125 ,(2012) , 10.5021/AD.2012.24.2.115
Rolf Hoffmann, Wolfgang Eicheler, Andrea Huth, Elke Wenzel, Rudolf Happle, Cytokines and growth factors influence hair growth in vitro: Possible implications for the pathogenesis and treatment of alopecia areata Archives of Dermatological Research. ,vol. 288, pp. 153- 156 ,(1996) , 10.1007/BF02505825
Ying Jin, Christina M. Mailloux, Katherine Gowan, Sheri L. Riccardi, Greggory LaBerge, Dorothy C. Bennett, Pamela R. Fain, Richard A. Spritz, NALP1 in Vitiligo-Associated Multiple Autoimmune Disease The New England Journal of Medicine. ,vol. 356, pp. 1216- 1225 ,(2007) , 10.1056/NEJMOA061592