Non-Hodgkin's lymphoma presenting with extradural spinal cord compression: functional outcome and survival.

作者: RA Eeles , P O'Brien , A Horwich , M Brada

DOI: 10.1038/BJC.1991.25

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摘要: Between 1971 and 1988, 20 patients with previously undiagnosed non-Hodgkin's lymphoma (NHL), of intermediate or high grade histology presented extradural spinal cord compression. All had decompressive surgery. The first treatment after surgery was chemotherapy in nine radiotherapy 11 patients. At presentation 15% were ambulant this improved to 55% surgery; urinary continence from 30 80%. Mobility sphincter control remained unchanged, regardless subsequent therapy. Chemotherapy as the initial modality surgery, either alone combination radiotherapy, did not jeopardise functional outcome. an independent prognostic factor for survival, when corrected age stage at (P = 0.04). NHL presenting compression should be based on histology, extent disease age, other sites presentation, but also take into consideration importance post-surgical mobility.

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