In vitro biomass production of liver-protective compounds fromGlobe artichoke (Cynara scolymus L.) and Milk thistle (Silybummarianum) plants -

作者: S. A. Bekheet

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摘要: The evolving importance of the plant secondary metabolites has in recent years resulted a great interest natural medicinal compounds, particularly their production by means cell culture technology. main advantage this technology is that it provides continuous, reliable source pharmaceuticals could be beneficial large-scale production. Globe artichoke and Milk thistle plants are considered important herbs producing active ingredients treat liver diseases. extract recommended for damage disease poor function. Cynarin, compounds several pharmaceutical actions such as protection re-growth cells. Otherwise, silymarin extracted from been used to hepatitis damage. This work discusses different approaches biotechnology biomass sources ingredients. Optimization physical conditions temperature, aeration, agitation light chemical factors like addition growth regulators precursors media vitro these have described. Moreover, transformed hairy roots cultures, caused infection Agrobacterium rhizogenes discussed an technique maximization

参考文章(40)
Johann Sonnenbichler, Isolde Sonnenbichler, Fortunato Scalera, Roland Weyhenmeyer, Stimulatory effects of silibinin and silicristin from the milk thistle Silybum marianum on kidney cells. Journal of Pharmacology and Experimental Therapeutics. ,vol. 290, pp. 1375- 1383 ,(1999)
F. Fraschini, G. Demartini, D. Esposti, Pharmacology of Silymarin Clinical Drug Investigation. ,vol. 22, pp. 51- 65 ,(2002) , 10.2165/00044011-200222010-00007
Nora Priolo, Cecilia Cimino, Francisco Spina, Claudia Natalucci, Sandra Vairo Cavalli, Callus culture for biomass production of milk thistle as a potential source of milk clotting peptidases Electronic Journal of Biotechnology. ,vol. 9, pp. 0- 0 ,(2006) , 10.4067/S0717-34582006000300012
Hsin-Sheng Tsay, Vanisree Mulabagal, PLANT CELL CULTURES AN ALTERNATIVE AND EFFICIENT SOURCE FOR THE PRODUCTION OF BIOLOGICALLY IMPORTANT SECONDARY METABOLITES 國際應用科學與工程學刊. ,vol. 2, pp. 29- 48 ,(2004)
Hassan Rahnama, T Hasanlou, Mohammad Reza Shams, Roshanak Sepehrifar, Silymarin production by hairy root culture of Silybum marianum (L.) Gaertn Iranian Journal of Biotechnology. ,vol. 6, pp. 113- 118 ,(2008)
Jonathan E. Brown, Catherine A. Rice-Evans, Luteolin-rich artichoke extract protects low density lipoprotein from oxidation In vitro Free Radical Research. ,vol. 29, pp. 247- 255 ,(1998) , 10.1080/10715769800300281
RHA El-Wahab, Mohamed S Zaghloul, Wafaa M Kamel, ARA Moustafa, None, Diversity and distribution of medicinal plants in North Sinai, Egypt African Journal of Environmental Science and Technology. ,vol. 2, pp. 157- 171 ,(2008) , 10.5897/AJEST.9000035
Skuntala Wilasrusmee, Gaurang Shah, Josephine Siddiqui, Chumpon Wilasrusmee, Dilip S. Kittur, Smita Kittur, David Bruch, Immunostimulatory effect of Silybum Marianum (milk thistle) extract. Medical Science Monitor. ,vol. 8, ,(2002)
L. Tůmová, J. Řimáková, J. Tůma, J. Dušek, SILYBUM MARIANUM IN VITRO FLAVONOLIGNAN PRODUCTION Plant Soil and Environment. ,vol. 52, pp. 454- 458 ,(2018) , 10.17221/3466-PSE