Original Article Correlation between VEGFR2 rs2071559 polymorphism and glioma risk among Chinese population

摘要: Objective: We investigated the correlation between vascular endothelial growth factor 2 (VEGFR2) poly- morphism and glioma risk among Chinese population. Method: Case-control study design was adopted, blood samples clinical data of 250 cases 260 control subjects were collected. Epidemiological question- naire survey performed, DNA extraction, concentration normalization packaging carried out using Qiagen Blood Kit. TaqMan method performed for VEGFR2 rs2071559 genotyping. Results: C allele genotype susceptibility contributing to (OR=1.813, 95% CI: 1.393- 2.359, P=0.014). CC genotypes associated with increased (OR=2.068, 1.164-3.674, P=0.014; Adjusted OR=1.883, 1.430~3.013, P=0.018). Conclusion: However, role polymorphism in remains be further clarified.