The use of monoclonal anti-T cell antibodies to study T cell imbalances in human diseases.

摘要: Monoclonal antibodies are now available to evaluate human T cell subsets by direct counting using indirect immunofluorescence analysis. The critical use of these has already permitted the delineation imbalances present in a number immunologically mediated diseases such as autoimmune haemolytic anaemia, chronic active hepatitis, myasthenia gravis, glomerulonephritides, multiple sclerosis, leprosy, or immunodeficiency syndromes. potential diagnostic and therapeutic application this new methodology emphasized.