Fusion of Cells for Virus Studies and Production of Cell Hybrids

摘要: Publisher Summary This chapter discusses fusion of cells for virus studies and production cell hybrids. Vertebrate can be fused in two ways, that is, by spontaneous or treatment with certain viruses. The former method requires mixed cultivation continuous lines cells. Spontaneous mating events occur low comparatively high frequency. ability to fuse is a property normal membranes, as it occurs pinocytosis phagocytosis the formation vacuole, giant macrophages reaction foreign bodies. However, mediated ultraviolet-inactivated Sendai generating experimental systems are useful studying fundamental problems biology, which approached no other way. viability heterokaryons hybrid demonstrates one point principle, biochemical similarity between vertebrate species far apart hen mouse, mouse man.