Protective effect of Woodfordia fruticosa flowers against acetaminophen-induced hepatic toxicity in rats.
作者： Yogesh Baravalia , Sumitra Chanda
DOI: 10.3109/13880209.2010.550057
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摘要: Context: The flowers of Woodfordia fruticosa Kurz. (Lythraceae) are commonly used for the treatment several ailments which includes rheumatism, leucorrhea, menorrhagia, asthma, liver disorder, and inflammatory conditions.Objective: To evaluate hepatoprotective property against acetaminophen-induced hepatic injury in rats.Material methods: Acetaminophen (3 g/kg bw)-induced hepatotoxicity study was carried out by observing effect methanol extract (400 600 mg/kg, bw) on some serum marker enzymes, albumin, blood urea nitrogen levels as well total protein, nonenzymetic glutathione reduced content, enzymatic antioxidant peroxidase, with histopathological evidence.Results discussion: Pretreatment rats effectively prevented damage indicated enzymes aspartate aminotransferase, alanine amin...
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