Simultaneous ESI-APCI(+) ionization and fragmentation pathways for nine benzodiazepines and zolpidem using single quadrupole LC-MS

作者: Toma Galaon , Catalina Vacaresteanu , Dan-Florin Anghel , Victor David

DOI: 10.1002/DTA.1526

关键词:

摘要: … Thus, the final method separated all analytes at minimum baseline resolution in less than 7.5 min using a Zorbax Eclipse Plus C18 column (150 × 4.6 mm, 3.5 µm) and 0.3% HCOOH / …

参考文章(29)
Valquiria AP Jabor, Eduardo B Coelho, Neife AG Dos Santos, Pierina S Bonato, Vera L Lanchote, None, A highly sensitive LC-MS-MS assay for analysis of midazolam and its major metabolite in human plasma: applications to drug metabolism. Journal of Chromatography B. ,vol. 822, pp. 27- 32 ,(2005) , 10.1016/J.JCHROMB.2005.05.011
Hans H. Maurer, Mass spectrometric approaches in impaired driving toxicology Analytical and Bioanalytical Chemistry. ,vol. 393, pp. 97- 107 ,(2009) , 10.1007/S00216-008-2338-8
Sophie Bourcier, Yannik Hoppilliard, Taraneh Kargar-Grisel, Jean Marie Pechiné, Felix Perez, Do thermally-labile 1,4-benzodiazepines rearrange under electrospray and particle bombardment? European Journal of Mass Spectrometry. ,vol. 7, pp. 359- 371 ,(2001) , 10.1255/EJMS.446
Ioannis I. Papoutsis, Sotirios A. Athanaselis, Panagiota D. Nikolaou, Constantinos M. Pistos, Chara A. Spiliopoulou, Constantinos P. Maravelias, Development and validation of an EI–GC–MS method for the determination of benzodiazepine drugs and their metabolites in blood: Applications in clinical and forensic toxicology Journal of Pharmaceutical and Biomedical Analysis. ,vol. 52, pp. 609- 614 ,(2010) , 10.1016/J.JPBA.2010.01.027
Stephane Pirnay, Françoise Hervé, Stéphane Bouchonnet, Bérengère Perrin, Frédéric J. Baud, Ivan Ricordel, Liquid chromatographic–electrospray ionization mass spectrometric quantitative analysis of buprenorphine, norbuprenorphine, nordiazepam and oxazepam in rat plasma Journal of Pharmaceutical and Biomedical Analysis. ,vol. 41, pp. 1135- 1145 ,(2006) , 10.1016/J.JPBA.2006.02.020
Tiago L. Laurito, Gustavo D. Mendes, Vincenzo Santagada, Giuseppe Caliendo, Maria Elisabete A. de Moraes, Gilberto De Nucci, Bromazepam determination in human plasma by high-performance liquid chromatography coupled to tandem mass spectrometry: a highly sensitive and specific tool for bioequivalence studies Journal of Mass Spectrometry. ,vol. 39, pp. 168- 176 ,(2004) , 10.1002/JMS.590
Saïd Kinani, Stéphane Bouchonnet, Nathalie Milan, Ivan Ricordel, A sensitive and selective method for the detection of diazepam and its main metabolites in urine by gas chromatography–tandem mass spectrometry Journal of Chromatography A. ,vol. 1141, pp. 131- 137 ,(2007) , 10.1016/J.CHROMA.2006.12.008
Kristina Y. Rust, Markus R. Baumgartner, Natascha Meggiolaro, Thomas Kraemer, Detection and validated quantification of 21 benzodiazepines and 3 "z-drugs" in human hair by LC-MS/MS. Forensic Science International. ,vol. 215, pp. 64- 72 ,(2012) , 10.1016/J.FORSCIINT.2011.07.052