Pharmacokinetics of clozapine and its metabolites in psychiatric patients: plasma protein binding and renal clearance
作者： Schaber , Stevens , Gaertner , Dietz , Breyer‐Pfaff
DOI: 10.1046/J.1365-2125.1998.00822.X
关键词:
摘要: Aims N-Desmethylclozapine and clozapine N-oxide are major metabolites of the atypical neuroleptic in humans undergo renal excretion. The aim this study was to investigate what extent elimination these urine contributes total fate patients how they handled by kidney.
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