Calculation of Normal Ranges by Methods Used for Resolution of Overlapping Gaussian Distributions

作者: E Melvin Gindler

DOI: 10.1093/CLINCHEM/16.2.124

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摘要: Distribution of a quantity, e.g. , concentration serum constituent, in typical general hospital population is considered. It assumed that the distribution within any subpopulation Gaussian and adjacent subpopulations overlap somewhat, presenting overlapping distributions. Bhattacharya’s procedure for resolving such distributions, based upon differentiation equation, applied to determination apparent normal range as well as, some cases, an abnormal range. probability paper used estimating conditions discussed under which this method may be expected give valid estimate. Use chi-square test evaluate long-term constancy clinical laboratory data distribution, abnormal, also

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