Bioactive biomaterials for controlling biofilms

摘要: Indwelling medical devices are a cornerstone of modern surgical practice, providing effective, cost-effective and often simple solutions for the management range clinical scenarios where support is required normal physiology body. However, their increasingly widespread use significantly compromised by propensity to become colonized microorganisms, leading device-associated infections, with at least half all incidences healthcare-associated infections in National Health Service (UK) now linked use. This chapter reviews processes such goes on discuss development emerging strategies which prevent microbial colonization, biofilm formation infection via coordination, control or triggered release antimicrobial agents from polymeric systems response various infection-associated triggers.