Host Response to Biomaterials

摘要: The implantation of a biomaterial-based device or drug carrier will elicit localized systemic inflammatory response. An immune response occurs regardless the method introduction biomaterial into body, as all methods insertion, including surgery and injection, result in disruption host’s tissue. extent response, however, is dependent upon location, procedure, compatibility biomaterial. In general, responses can be classified acute chronic, defined primarily by duration type cells infiltrating tissue to pro-inflammatory signals. This chapter discusses general process chronic gives details on key soluble blood plasma factors involved. Information also provided design approaches employed minimizing