Correlation of histological inflammation in needle biopsy specimens with serum prostate- specific antigen levels in men with negative biopsy for prostate cancer

作者: Koichi Okada , Munekado Kojima , Yoshio Naya , Kazumi Kamoi , Keiichi Yokoyama

DOI: 10.1016/S0090-4295(00)00519-7

关键词:

摘要: Abstract Objectives. To reveal the possible contribution of histological inflammation within prostate to abnormal elevation serum prostate-specific antigen (PSA) levels in patients with needle biopsy negative for cancer. Methods. We reviewed specimens obtained 93 patients. The degree acute and chronic as evaluated histologically was compared PSA conjunction age volume. Results. Both ( P Conclusions. Histologically defined is a significant contributor elevated levels, especially small prostates. In assessment results cancer, it might be helpful evaluate inflammation, terms necessity subsequent repeated biopsies.

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