Neuropsychological correlates of insight in obsessive-compulsive disorder.
作者： Himani Kashyap , JK Kumar , Thennarasu Kandavel , YC Janardhan Reddy
DOI: 10.1111/J.1600-0447.2012.01845.X
关键词:
摘要: Kashyap H, Kumar JK, Kandavel T, Reddy YCJ. Neuropsychological correlates of insight in obsessive–compulsive disorder. Objective: There are limited data on neuropsychological poor disorder (OCD). We hypothesize that may be associated with greater impairment tasks conflict resolution/response inhibition and possibly a task verbal learning memory. Method: Insight functions were assessed 150 subjects DSM-IV OCD. The 177 healthy control used for comparison. Results: score correlated significantly the Stroop Interference Test (P = 0.002), showed trends significance Controlled Oral Word Association (COWA) average fluency (P = 0.021) delayed recall Auditory Verbal Learning (AVLT) memory (P = 0.015). On regression analysis, AVLT recall, COWA average, Matrix score, Yale-Brown Obsessive–Compulsive Scale total current antipsychotic use emerged as significant predictors poorer insight. Conclusion: Poor is impairments inhibition, memory, fluency. Individuals have difficulty appropriately processing conflicting information, updating their corrective then accessing this information to modify irrational beliefs.
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