CPAP increases exercise tolerance in obese subjects with obstructive sleep apnea.

摘要: Summary Obese subjects commonly suffer from exertional dyspnea and exercise intolerance. Preliminary evidence suggests that treatment with nocturnal continuous positive airway pressure (nCPAP) may improve in obese patients obstructive sleep apnea (OSA), but the effect on tolerance is unknown. This study sought to investigate whether nCPAP improves OSA. prescribed for moderate/severe OSA without cardiopulmonary disease were recruited. Patients completed a constant-load test Baseline Transitional Dyspnea Index questionnaires (BDI/TDI) at baseline after one three months of nCPAP. Primary outcome was change time months. Secondary outcomes included changes isotime dyspnea, leg fatigue BDI/TDI score Fifteen (body mass index = 43 kg m -2 , apnea-hypopnea index = 49 . hr −1 ) studied. Constant-load increased by 2.0 min (40%, p  = 0.02) month 1.8 min (36%,  = 0.04) At months, decreased 1.4 (  = 0.17) 2 units  = 0.04), 1.2  = 0.18)  = 0.02), respectively. scores 2.7  = 0.001) 4.5 points Nocturnal CPAP Effects chronic seen nCPAP, while exertional dyspnea only improved