作者: Olga G. Troyanskaya , Robert B. Darnell , Chandra L. Theesfeld , Aaron K. Wong , Jian Zhou
DOI: 10.1038/S41588-020-00761-3
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摘要: … LD score regression with our deep learning framework … variants into four different MAF bins (>0.05, 0.05–0.01, 0.01–0.001, … modeled using a Fisher polygenic model with trait heritability …