Effect of repetitive SCUBA diving on humoral markers of endothelial and central nervous system integrity

摘要: During SCUBA diving decompression, there is a significant gas bubble production in systemic veins, with rather frequent crossover to arterial side even asymptomatic divers. The aim of the current study was investigate potential changes humoral markers endothelial and brain damage (endothelin-1, neuron-specific enolase S-100β) after repetitive concomitant assessment venous subsequent arterialization. Sixteen male divers performed four open-water no-decompression dives 18 msw (meters sea water) lasting 49 min consecutive days during which they moderate-level exercise. Before 1 4 blood drawn, arterialization were echocardiographically evaluated. In addition, control dive 5 msw same duration, water temperature exercise load. caused arterializations six 4. Blood levels endothelin-1 did not change diving, but S-100β significantly elevated both dive. Creatine kinase activity following also increased. Although serum increased increase creatine control, almost bubble-free, suggests extracranial release S-100β, most likely from skeletal muscles. Therefore, despite sporadic 18 msw, found no signs neurons or blood–brain barrier.