摘要: Publisher Summary Amylin enhances the uptake of certain amino acids, crosses blood–brain barrier, and increases body temperature. The physiological significance these responses is currently unclear. Centrally administered amylin reduces locomotor exploratory behavior. alone analgesic when peripherally via a nonopiate pathway. Banks coworkers studied iodinated rat in brains ICR mice at brain regions outside circumventricular organs, where was known to bind which diffusional barrier reduced. rate loss behaviors (extinction) upon cessation conditioning stimuli found be dose-dependently faster, if immediately given intracerebroventricularly CFY rats implanted with cannulae. In another study, deletion gene displayed reduced pain response paw formalin test, leading conclusion that has pronociceptive function primary sensory neurons.