Central nicotinic receptor blockade inhibits emotionally conditioned pressor responses in rats.
作者： T. Kubo , Y. Katsumata , R. Fukumori , K. Taguchi , Y. Hagiwara
DOI: 10.1007/BF01919539
关键词:
摘要: A conditioned stimulus previously paired with electric footshock produced an increase in blood pressure conscious, freely moving rats. The pressor response was reproducible. Intracerebroventricular injection of the nicotinic receptor antagonists hexamethonium (1–10 μg) or pentolinium (10 but not muscarinic antagonist methylatropine (3 inhibition response, whereas intraarterial did affect response. Intraventricular cholinesterase inhibitor physostigmine (3–10 enhancement These results are consistent possibility that central receptors play a role expression emotionally
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