Introduction to a Compendium on Hypertension

摘要: Hypertension is by far the most common disease that affects human beings, its high prevalence involving both sexes and extending to either industrialized developing countries.1 Compared with normotensives, individuals a blood pressure stand much greater chance of having during their life stroke, coronary heart disease, or renal failure, peripheral artery disease,2 substantially higher risk also atrial fibrillation,3 deterioration cognitive function, dementia.4 The multifold important contribution hypertension cardiovascular account for position as top contributor burden worldwide.5 Despite extensive research cause causes in given patient remain instances unclear today they were decades ago. Yet, data have been obtained basic clinical studies provided considerable knowledge factors may be potentially involved well molecular, humoral, neural, structural mechanisms through which increase occur. aim this compendium, first devoted Circulation Research , offer clinicians investigators critical review knowledge, covering large spectrum data, is, from genetic molecular integrated pathophysiology, epidemiology, diagnosis, treatment. Rahimi et al6 open series survey epidemiology hypertension. Evidence progressive diseases increasing values reviewed together issues great current interest …