The Fruit Fly Drosophila melanogaster as a Model for Aging Research.

摘要: : Average human life expectancy is increasing and so the impact on society of aging age-related diseases. Here we highlight recent advances in diverse multidisciplinary field research, focusing fruit fly Drosophila melanogaster, an excellent model system which to dissect genetic molecular basis processes. The conservation disease genes D. melanogaster allows functional analysis orthologues implicated models have been developed for a variety processes disorders, including stem cell decline, Alzheimer's disease, cardiovascular deterioration. Understanding detailed events involved normal diseases could facilitate development strategies treatments that reduce their impact, thus improving health longevity.